Uterus Cancer

Uterus cancer is the most common genital cancer in women. It occurs most commonly in 60 to 70 years. Uterus cancer patients usually present in very early stage of disease.

Risk Factors
  • Early puberty and late menopause
  • Nulliparous women
  • Diabets Mellitus
  • Hypertensive
  • Polycystic ovarian disease
  • Prior pelvic Radiation therapy
  • Family history
Clinical presentation
  • Abnormal vaginal bleeding
  • Post menopausal bleeding
  • Pain in abdomen
Evaluation
  • Endometrial biopsy
  • Dilatation and curettage
  • MRI pelvis
  • CT scan chest, abdomen in advanced cases
Staging
  • Very early stage – disease confined only to uterus
  • Early stage- Disease confined to uterus and cervix
  • Advanced stage – Disease reaching outer layers of uterus, ovaries and nodes
  • Very advanced stage- Disease spread to urinary bladder, rectum and nodes
Treatment
  • Very early stage only simple surgery like removal of uterus is sufficient and it can be done by Laparoscopy also.
  • early stages she may need radiation and chemotherapy, in addition to surgery
  • Advanced stage – Chemotherapy and radiation therapy. Role of surgery is limited
  • Very advanced stage- Palliative chemotherapy, radiation therapy.